Actara 25 WG Induced Histopathological Changes in Thyroid and Intestine of Swiss Albino Mice

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Year:
2017
Type of Publication:
Article
Keywords:
Actara 25wg, Histopathology, Insecticide, Interstitialhaemorrhage
Authors:
Haloi, Dr. Akshay Kr.; Barman, Trishna; Kalita, Dr. Evarani; Deka, Punam
Journal:
IJRAS
Volume:
4
Number:
5
Pages:
226-230
Month:
September
ISSN:
2348-3997
Abstract:
ACTARA 25 WG is a unique systemic insecticide used as a tea garden insecticide to kill the unwanted pests that harm the tea plant. It mainly destroys bugs, beetles etc provides excellent elimination of a broad range of foliar and soil pest with a fast rate. The present study investigated the toxic effect of Actara-25 wg. On the intestine and thyroid of swiss albino mice. Four adult mice are divided into two groups of which Group-1 consists of four untreated mice maintained in laboratory condition and the Group-2 consists of four mice in same condition but given daily Actaraat the dose of 2mg/gm body weight for a period of 14 days via oral route. Histopathological study was performed following the processes of microtomyas per the method of Luna et al., 1968 [1]. Results shows pathological changes as loosened muscular part, cytoplasmic degranulation, vacuolation, nucleopyknosis along with brokenvilli tips, disrupted and separated serosa in intestine. In thyroid tissues changes mainly occur as follicular enlargement, disruption of connective tissue, interstitial haemorrhage, congested blood vessels. The oral administration of Actara-25wg gives an inflammatory process in intestine and thyroid that constitute a toxicity sign in swiss albino mice
Full text: IJRAS_597_FINAL.pdf

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